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partial agonism造句

例句與造句

  1. Varenicline's partial agonism on the ? 4 ? 2 receptors rather than nicotine's full agonism produces less effect of dopamine release than nicotine's.
  2. It was found that partial agonism results from deficiency in the first step, and that the opening and shutting steps are essentially the same for both full and partial agonists.
  3. Unlike most current antipsychotics, such as haloperidol, risperidone, and olanzapine, lumateperone does not disrupt signaling, a property which is likely due to partial agonism of presynaptic D 2 receptors.
  4. Moreover, due to partial agonism of the KOR, where it appears to possess significantly greater intrinsic activity relative to the MOR, diprenorphine can produce sedation as well as, in humans, hallucinations.
  5. 4-" O "-Methylhonokiol is a potent partial agonism via different pathways ( cAMP and Ca 2 + ) and potently inhibits osteoclastogenesis . 4-O-Methylhonokiol further attenuates memory impairment in presenilin 2 mutant mice through reduction of oxidative damage and inactivation of astrocytes and the ERK pathway.
  6. It's difficult to find partial agonism in a sentence. 用partial agonism造句挺難的
  7. These super-potent opioids, with the single exception of buprenorphine ( which has an improved safety-profile due to its partial agonism character ), are not used in humans because the dose for a human is so small that it would be difficult to measure properly, so there is an excessive risk of overdose leading to fatal respiratory depression.
  8. The fact that receptor conformation ( state ) would affect binding affinity of a ligand was used to explain a mechanism of partial agonism of receptors by del Castillo & Katz in 1957 was based on their work on the action of acetylcholine at the motor endplate The del Castillo-Katz mechanism divorces the binding step ( that can be made by agonists as well as antagonists ) from the receptor activation step ( that can be only exerted by agonists ), describing them as two independent events.

相鄰詞匯

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